Assuming that the early development for season 2 has already occurred in the production room, fans could see The Legend of Vox Machina return as soon as Q4 2022.
As shown in the series, Orthax's pact does not simply end when all of the targets are killed.
A more direct reference comes in episode 8 when the team goes up against several magically animated suits of armor that bear a striking resemblance to Alphonse Elric from the Full Metal Alchemist franchise.